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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLTCL1
All Species:
12.73
Human Site:
Y161
Identified Species:
23.33
UniProt:
P53675
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P53675
NP_009029.3
1640
187030
Y161
I
H
Y
R
T
D
E
Y
Q
K
W
L
L
L
V
Chimpanzee
Pan troglodytes
XP_001154119
1640
186911
Y161
I
H
Y
R
T
D
E
Y
Q
K
W
L
L
L
V
Rhesus Macaque
Macaca mulatta
XP_001108544
1639
187872
K161
I
N
Y
R
T
D
A
K
Q
K
W
L
L
L
T
Dog
Lupus familis
XP_534763
1673
189990
Y161
I
H
Y
R
T
D
E
Y
Q
K
W
L
L
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q68FD5
1675
191538
K161
I
N
Y
R
T
D
A
K
Q
K
W
L
L
L
T
Rat
Rattus norvegicus
P11442
1675
191580
K161
I
N
Y
R
T
D
A
K
Q
K
W
L
L
L
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509659
1675
191558
K161
I
N
Y
R
T
D
A
K
Q
K
W
L
L
L
T
Chicken
Gallus gallus
XP_415060
1672
190998
H161
I
N
Y
R
T
D
E
H
Q
K
W
L
L
L
I
Frog
Xenopus laevis
NP_001085860
1675
191412
K161
I
N
Y
R
T
D
A
K
Q
K
W
L
L
L
T
Zebra Danio
Brachydanio rerio
XP_699126
1677
191618
K161
I
N
Y
R
T
D
A
K
Q
K
W
L
L
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P29742
1678
191159
S161
I
N
Y
R
C
N
A
S
Q
Q
W
L
L
L
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34574
1681
191524
E159
I
N
Y
R
A
D
A
E
N
K
W
L
V
L
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22137
1653
187216
N164
I
N
F
V
A
N
K
N
L
D
W
F
A
V
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
84.6
90.6
N.A.
83
82.9
N.A.
82.9
88.1
82.5
83.3
N.A.
75.3
N.A.
67.8
N.A.
Protein Similarity:
100
99.6
93.2
94.8
N.A.
91.5
91.4
N.A.
91.3
93.9
91.2
91.1
N.A.
87
N.A.
82.1
N.A.
P-Site Identity:
100
100
73.3
93.3
N.A.
73.3
73.3
N.A.
73.3
80
73.3
73.3
N.A.
60
N.A.
53.3
N.A.
P-Site Similarity:
100
100
80
100
N.A.
80
80
N.A.
80
100
80
86.6
N.A.
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
69.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
0
62
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
85
0
0
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
31
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
24
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
31
% I
% Lys:
0
0
0
0
0
0
8
47
0
85
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
0
93
85
93
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
77
0
0
0
16
0
8
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
85
8
0
0
0
0
0
% Q
% Arg:
0
0
0
93
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
39
% T
% Val:
0
0
0
8
0
0
0
0
0
0
0
0
8
8
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% W
% Tyr:
0
0
93
0
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _